BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	18q21
Chromosome Position	chr18:45900000-63900000
No. of Studies (Positive/Negative/Trend)	3(2/1/0)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Bennett, P.,2002	D18S474	Linkage analysis: LOD = 0.59, Multipoint MLS(narrow model) =...... Linkage analysis: LOD = 0.59, Multipoint MLS(narrow model) = 1.23 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Nwulia, E. A.,2007	D18S814	Non-parametric multipoint linkage analysis: NPL = 3.56, P-va...... Non-parametric multipoint linkage analysis: NPL = 3.56, P-value = 0.0004 More...	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
Cheng, R.,2006	D18S851	Two point parametric linkage analysis: LOD = 3.61, theta = 0...... Two point parametric linkage analysis: LOD = 3.61, theta = 0, Model BP1, dom More...	Significant linkage was found in this region. Significant linkage was found in this region.	Positive

Region related genes (count: 10)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
BCL2	B-cell CLL/lymphoma 2	18q21.3	2(0/2/0)
CCDC68	coiled-coil domain containing 68	18q21	1(1/0/0)
MYO5B	myosin VB	18q	2(1/0/1)
CCBE1	collagen and calcium binding EGF domains 1	18q21.32	1(0/1/0)
TXNL1	thioredoxin-like 1	18q21.31	1(0/0/1)
WDR7	WD repeat domain 7	18q21.31	1(0/1/0)
TCF4	transcription factor 4	18q21.1	6(1/5/0)
ACAA2	acetyl-CoA acyltransferase 2	18q21	1(1/0/0)
DCC	DCC netrin 1 receptor	18q21.1	2(1/1/0)
SCARNA17	small Cajal body-specific RNA 17	18q21.1	1(1/0/0)

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Region: chr18:45900000..63900000 View in gBrowse