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GO Report
Basic Info
| ID | GO:0005249 |
|---|---|
| Name | voltage-gated potassium channel activity |
| Type | molecular function |
| No. of Genes in BDgene | 5 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| VOLTAGE GATED POTASSIUM CHANNEL ACTIVITY | i-GSEA analysis | Smith, E. N., Mol Psychiatry, 2009 | dbGaP GAIN EA | i-GSEA by using i-GSEA4GWAS | P-value< 0.001, FDR=0.018111112 | Link in i-GSEA4GWAS |
| GO: 0005249: voltage-gated K+ channel act. | PBA paper | Askland, K.,2009 | NIMH | Fisher's exact test | Results given for gene sets with P < 0.05 from the NIMH PBA; Molecular function | |
| GO: 0005249: voltage-gated K+ channel act. | PBA paper | Askland, K.,2009 | WTCCC Bayesian genotypic | Fisher's exact test | P < 0.05 from the WTCCC PBAs |
GO related genes in BDgene (count: 5)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | 2q24.3 | 3(2/0/1) | IBA |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 7q31 | 1(1/0/0) | IDA[24811166]; ISS; NAS[11102480] |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 | 20q13.33 | 1(1/0/0) | TAS[9677360] |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | 8q24 | 4(3/0/1) | TAS[9677360] |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic | 11q23.1-q23.2 | 2(1/1/0) | IEA |