SNP Report

Basic Info

Name	rs2276914 dbSNP Ensembl
Location	chr4:186151778 - 186151778(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.11222
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000508379); intron_variant(ENST00000227065, ENST00000356371, ENST00000389354, ENST00000502970, ENST00000503432, ENST00000504330, ENST00000509574, ENST00000510790, ENST00000513030, ENST00000513212, ENST00000514153, ENST00000514829, ENST00000515078); non_coding_transcript_variant(ENST00000513030, ENST00000513212, ENST00000514829, ENST00000515078)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Blair, I. P.,2005	G/A		X² goodness of fit tests: MAF=0.14, Genotype P-va...... X² goodness of fit tests: MAF=0.14, Genotype P-value = 0.47, Allele P-value = 0.61 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
FAM149A	family with sequence similarity 149, member A	4q35.1	1(0/1/0)

SNPs in LD with rs2276914 (count: 7) View in gBrowse (chr4:186139930..186156052 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4862650	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs4862653	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.856[TSI]
rs6858112	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.879[CEU]; 0.847[TSI]
rs13141920	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.879[CEU]; 0.847[TSI]
rs7684126	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs2276912	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs7668227	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.879[CEU]; 0.847[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)