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KEGG Pathway Report
Basic Info
| ID | hsa04115 |
|---|---|
| Name | p53 signaling pathway |
| No. of Genes in BDgene | 4 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| p53 signaling pathway | PBA paper | Chang, S., 2015 | group B | i-GSEA4GWAS v2, GenGen | FDR=0.109 (B) by i-GSEA4GWAS v2; FDR=0.003 (B) by GenGen | |
| p53 signaling pathway | PBA paper | Chen, L., 2009 | WTCCC | Prioritizing Risk Pathways fusing SNPs and pathways (PRP) | risk score=0.81 |
Pathway related genes in BDgene (count: 4)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| TP53I3 | tumor protein p53 inducible protein 3 | 2p23.3 | 1(1/0/0) |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 12q23.2 | 1(1/0/0) |
| STEAP3 | STEAP family member 3, metalloreductase | 2q14.2 | 1(0/0/1) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 9p21 | 1(1/0/0) |