Disease |
SNP |
Related Gene(s) |
Statistical Values |
Description |
Result Category |
SZ |
rs17487223 |
CHRNB4
|
P-value=0.03, OR=1.08, 95% CI=(0.98-1.14) in SZD; P-value=0.009, OR=1.07, 95% CI=(1.02-1.13) in SZD + BD; P-value=0.018, OR=1.21, 95% CI=(1.06-1.43) in SZD with the presence of negative symptoms of schizophrenia |
Two variants, rs8040868 and rs17487223, were significantly associated with risk for schizophrenia. When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. |
Positive |
SZ |
rs8040868 |
CHRNA3
|
P-value=0.004, OR=1.09, 95% CI=(1.03-1.16) in SZD; P-value=0.007, OR=1.07, 95% CI=(1.02-1.12) in SZD + BD; P-value=0.02, OR=1.16, 95% CI=(1.02-1.31) in SZD with the presence of negative symptoms of schizophrenia |
Two variants, rs8040868 and rs17487223, were significantly associated with risk for schizophrenia. When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. |
Positive |
SZ |
rs951266 |
CHRNA5
|
P-value=0.15, OR=1.05, 95% CI=(1.02-1.18) in SZD; P-value=0.009, OR=1.07, 95% CI=(1.02-1.13) in SZD + BD; P-value=0.017, OR=1.19, 95% CI=(1.03-1.37) in SZD with the presence of negative symptoms of schizophrenia |
When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. |
Positive |
SZ |
rs1051730 |
CHRNA3
|
P-value=0.19, OR=1.05, 95% CI=(0.97-1.13) in SZD; P-value=0.08, OR=1.05, 95% CI=(0.99-1.1) in SZD + BD; P-value=0.019, OR=1.19, 95% CI=(1.03-1.37) in SZD with the presence of negative symptoms of schizophrenia |
A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. |
Positive |
SZ |
rs16969968 |
CHRNA3
CHRNA5
|
P-value=0.09, OR=1.06, 95% CI=(0.97-1.13) in SZD; P-value=0.04, OR=1.06, 95% CI=(1-1.11) in SZD + BD; P-value=0.07, OR=1.15, 95% CI=(0.99-1.34) in SZD with the presence of negative symptoms of schizophrenia |
When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. |
Positive |