BDgene

SNP Report

Basic Info
Name rs11622475 dbSNP Ensembl
Location chr14:104042739 - 104042739(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.248203
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000339063, ENST00000409874, ENST00000557332)
No. of Studies 4 (Positive: 0; Negative: 1; Trend: 3)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 4)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Jiang, Y.,2011 Non-weighted test under H0: P-value(additive)=0.0000021, P-v...... Non-weighted test under H0: P-value(additive)=0.0000021, P-value(dominant)=0.0000022, P-value(recessive)=0.0195; weighted test under H'0: P-value(additive)=0.00000778, P-value(dominant)=0.00000907, P-value(recessive)=0.0142; logistic regression: P-value(additive)=0.00000241, P-value(dominant)=0.00000526, P-value(recessive)=0.00926 More... Suggestive association was found. Suggestive association was found. Trend
Feng, T.,2010 Fisher's exact tests: Empirical P-value(1, 000, 000 permutat...... Fisher's exact tests: Empirical P-value(1, 000, 000 permutations)=0.000027 More... Suggestive association was found. Suggestive association was found. Trend
The Wellcome Trust Case Control Consortium, 2007 C/T C Genotypic P-value = 8.14E-06; Heterozygote OR (95%CI)=1.13 ...... Genotypic P-value = 8.14E-06; Heterozygote OR (95%CI)=1.13 (0.89-1.44); Homozygote OR (95%CI)=1.47 (1.17-1.86) More... showing moderate evidence of association with BD showing moderate evidence of association with BD Trend
Ollila, H. M.,2009 C/T FBAT: P-value = 0.781012 FBAT: P-value = 0.781012 No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TDRD9 tudor domain containing 9 14q32.33 3(1/1/1)

SNPs in LD with rs11622475 (count: 13) View in gBrowse (chr14:103898973..104060861 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 13)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)