BDgene

Region Report

Basic Info
Region Name 13q32
Chromosome Position chr13:98700000-101100000
No. of Studies (Positive/Negative/Trend)  9(2/3/4)

Region related studies (count: 9)
Reference Markers Statistical Values Author Comments Result Category
Xu, H.,2011 D13S779, D13S781 Family-Based Association: For marker D13S779, for BP2, allel...... Family-Based Association: For marker D13S779, for BP2, allele 5, Z-score = 2.3, P-value = 0.021458, Perm.P-value = 0.018622; Linkage study: For marker D13S779, for BP2, ASP model, LOD = 0 for New pedigrees(N = 16), LOD = 2.09 for all pedigrees(N = 56); For marker D13S781, ASP model, LOD = 0.13 for New pedigrees(N = 16), LOD = 2.69 for all pedigrees(N = 56); More... Significant associations were found in BP2. Significant associations were found in BP2. Positive
Savitz, J.,2007 D13S1298, D13S1271, D13S1284 Combined Merlin-SimWalk2 Analyses: For marker D13S1298, NPL-...... Combined Merlin-SimWalk2 Analyses: For marker D13S1298, NPL-pair = 0.29, P-value = 0.5151; For marker D13S1271, NPL-pair = 1.2, P-value = 0.063; For marker D13S1284, NPL-pair = 0.51, P-value = 0.3079 More... No significant linkage was found in this region. No significant linkage was found in this region. Negative
Xu, H.,2010 D13S779, D13S781 Association analysis: For marker D13S779, for BP2, allele 5...... Association analysis: For marker D13S779, for BP2, allele 5, z-score = 2.3, FBAT P-value = 0.021458, perm P-value = 0.018622; linkage study: For marker D13S779, for BP2, ASP model, LOD = 0 in new pedigrees(N = 16); LOD = 2.09 in all pedigrees(N = 56); For marker D13S781, for BP2, ASP model, LOD = 0.13 in new pedigrees(N = 16); LOD = 2.69 in all pedigrees(N = 56) More... Significant associations were found in BP2. Significant associations were found in BP2. Positive
Liu, J.,2003 D13S779 Multipoint ASP results: LOD = 2.2, Model BP2 Multipoint ASP results: LOD = 2.2, Model BP2 Suggestive linkage was found in this region. Suggestive linkage was found in this region. Trend
Liu, C.,2001 D13S122, D13S71, D13S154, D13S1241, D13S793, D13S786, D13S159, D13S1240, D13S779, D13S225, D13S1266, D13S280, D13S158, D13S274, D13S1252, D13S1271 Nonparametric Single-Point Linkage Analyses: For marker D13S...... Nonparametric Single-Point Linkage Analyses: For marker D13S1252, ASM I , LOD = 2.31, P-value = 0.00055; ASM II, LOD = 2.58, P-value = 0.00028; For marker D13S1271, ASM I , LOD = 2.7, P-value = 0.00021; ASM II, LOD = 2.54, P-value = 0.00031 More... Suggestive linkage was found in this region. Suggestive linkage was found in this region. Trend
Cheng, R.,2006 D13S779 Two point parametric linkage analysis: LOD = 1.04, theta = 0...... Two point parametric linkage analysis: LOD = 1.04, theta = 0, Model BP1, rec More... No significant linkage was found in this region. No significant linkage was found in this region. Negative
Shaw, S. H.,2003 D13S800, D13S317, D13S793, D13S128, D13S770, D13S1240, D13S779, D13S225, D13S173, D13S796, D13S285, D13S154 For marker D13S154, For 32 pedigrees: Parametric linkage ana...... For marker D13S154, For 32 pedigrees: Parametric linkage analysis: BP only, Z-max = 2.29, theta = 0.1; Nonparametric linkage analysis: BP only, LOD = 0.65, P-value = 0.04; For 52 pedigrees: Parametric linkage analysis: BP only, Z-max = 2.83, theta = 0.1; Nonparametric linkage analysis: BP only, LOD = 1.09, P-value = 0.01 More... Suggestive linkage was found in this region under two differ...... Suggestive linkage was found in this region under two different diagnostic models. More... Trend
Cassidy, F.,2007 D13S779 Multipoint Linkage Analysis: Broad model, NPL = 1.75457, P-v...... Multipoint Linkage Analysis: Broad model, NPL = 1.75457, P-value = 0.039028; Pairwise Linkage Analysis: Broad model, NPL = 2.15582, P-value = 0.015295; Structure-Guided Linkage Analysis: Broad model: NPL = 2.25, P-value = 0.012 for all families.; NPL = 1.65, P-value = 0.049 for families.; Narrow model: NPL = 0.89, P-value = 0.19 for all families.; NPL = 0.69, P_value = 0.25 for 60% homogeneous families. More... There is a trend for Significant linkage. There is a trend for Significant linkage. Trend
Greenwood, T. A.,2012 D13S225 Linkage analysis: for BD+MDD, LOD = 1.28 Linkage analysis: for BD+MDD, LOD = 1.28 No significant linkage was found in this region. No significant linkage was found in this region. Negative

Region related genes (count: 3)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TM9SF2 transmembrane 9 superfamily member 2 13q32.2 1(0/0/1)
ZIC2 Zic family member 2 13q32 1(0/1/0)
DOCK9 dedicator of cytokinesis 9 13q32.3 1(1/0/0)

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Region: chr13:98700000..101100000 View in gBrowse
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