BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	13q32
Chromosome Position	chr13:98700000-101100000
No. of Studies (Positive/Negative/Trend)	9(2/3/4)

Region related studies (count: 9)

Reference	Markers	Statistical Values	Author Comments	Result Category
Xu, H.,2011	D13S779, D13S781	Family-Based Association: For marker D13S779, for BP2, allel...... Family-Based Association: For marker D13S779, for BP2, allele 5, Z-score = 2.3, P-value = 0.021458, Perm.P-value = 0.018622; Linkage study: For marker D13S779, for BP2, ASP model, LOD = 0 for New pedigrees(N = 16), LOD = 2.09 for all pedigrees(N = 56); For marker D13S781, ASP model, LOD = 0.13 for New pedigrees(N = 16), LOD = 2.69 for all pedigrees(N = 56); More...	Significant associations were found in BP2. Significant associations were found in BP2.	Positive
Savitz, J.,2007	D13S1298, D13S1271, D13S1284	Combined Merlin-SimWalk2 Analyses: For marker D13S1298, NPL-...... Combined Merlin-SimWalk2 Analyses: For marker D13S1298, NPL-pair = 0.29, P-value = 0.5151; For marker D13S1271, NPL-pair = 1.2, P-value = 0.063; For marker D13S1284, NPL-pair = 0.51, P-value = 0.3079 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Xu, H.,2010	D13S779, D13S781	Association analysis: For marker D13S779, for BP2, allele 5...... Association analysis: For marker D13S779, for BP2, allele 5, z-score = 2.3, FBAT P-value = 0.021458, perm P-value = 0.018622; linkage study: For marker D13S779, for BP2, ASP model, LOD = 0 in new pedigrees(N = 16); LOD = 2.09 in all pedigrees(N = 56); For marker D13S781, for BP2, ASP model, LOD = 0.13 in new pedigrees(N = 16); LOD = 2.69 in all pedigrees(N = 56) More...	Significant associations were found in BP2. Significant associations were found in BP2.	Positive
Liu, J.,2003	D13S779	Multipoint ASP results: LOD = 2.2, Model BP2 Multipoint ASP results: LOD = 2.2, Model BP2	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Liu, C.,2001	D13S122, D13S71, D13S154, D13S1241, D13S793, D13S786, D13S159, D13S1240, D13S779, D13S225, D13S1266, D13S280, D13S158, D13S274, D13S1252, D13S1271	Nonparametric Single-Point Linkage Analyses: For marker D13S...... Nonparametric Single-Point Linkage Analyses: For marker D13S1252, ASM I , LOD = 2.31, P-value = 0.00055; ASM II, LOD = 2.58, P-value = 0.00028; For marker D13S1271, ASM I , LOD = 2.7, P-value = 0.00021; ASM II, LOD = 2.54, P-value = 0.00031 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Cheng, R.,2006	D13S779	Two point parametric linkage analysis: LOD = 1.04, theta = 0...... Two point parametric linkage analysis: LOD = 1.04, theta = 0, Model BP1, rec More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Shaw, S. H.,2003	D13S800, D13S317, D13S793, D13S128, D13S770, D13S1240, D13S779, D13S225, D13S173, D13S796, D13S285, D13S154	For marker D13S154, For 32 pedigrees: Parametric linkage ana...... For marker D13S154, For 32 pedigrees: Parametric linkage analysis: BP only, Z-max = 2.29, theta = 0.1; Nonparametric linkage analysis: BP only, LOD = 0.65, P-value = 0.04; For 52 pedigrees: Parametric linkage analysis: BP only, Z-max = 2.83, theta = 0.1; Nonparametric linkage analysis: BP only, LOD = 1.09, P-value = 0.01 More...	Suggestive linkage was found in this region under two differ...... Suggestive linkage was found in this region under two different diagnostic models. More...	Trend
Cassidy, F.,2007	D13S779	Multipoint Linkage Analysis: Broad model, NPL = 1.75457, P-v...... Multipoint Linkage Analysis: Broad model, NPL = 1.75457, P-value = 0.039028; Pairwise Linkage Analysis: Broad model, NPL = 2.15582, P-value = 0.015295; Structure-Guided Linkage Analysis: Broad model: NPL = 2.25, P-value = 0.012 for all families.; NPL = 1.65, P-value = 0.049 for families.; Narrow model: NPL = 0.89, P-value = 0.19 for all families.; NPL = 0.69, P_value = 0.25 for 60% homogeneous families. More...	There is a trend for Significant linkage. There is a trend for Significant linkage.	Trend
Greenwood, T. A.,2012	D13S225	Linkage analysis: for BD+MDD, LOD = 1.28 Linkage analysis: for BD+MDD, LOD = 1.28	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TM9SF2	transmembrane 9 superfamily member 2	13q32.2	1(0/0/1)
ZIC2	Zic family member 2	13q32	1(0/1/0)
DOCK9	dedicator of cytokinesis 9	13q32.3	1(1/0/0)

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Region: chr13:98700000..101100000 View in gBrowse