BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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GO Report

Basic Info

ID	GO:0005085
Name	guanyl-nucleotide exchange factor activity
Type	molecular function
No. of Genes in BDgene	3
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
GO: 0005085: guanyl-nucleotide exchange factor act.	PBA paper	Askland, K.,2009	WTCCC Frequentist genotypic	Fisher's exact test	P < 0.05 from the WTCCC PBAs
GO: 0005085: guanyl-nucleotide exchange factor act.	PBA paper	Askland, K.,2009	WTCCC Bayesian genotypic	Fisher's exact test	P < 0.05 from the WTCCC PBAs

GO related genes in BDgene (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
TRIO	trio Rho guanine nucleotide exchange factor	5p14-p15.1	1(0/1/0)	TAS[8643598]
TIAM2	T-cell lymphoma invasion and metastasis 2	6q25	1(1/0/0)	TAS[10512681]
DOCK3	dedicator of cytokinesis 3	3p21	1(0/1/0)	IEA