Gene Report

Basic Info
Approved Symbol DBP
Symbol Alias DABP
Approved Name D site of albumin promoter (albumin D-box) binding protein
Location 19q13.33
Position chr19:48630030-48637438, -1
External Links HGNC: 2697
Entrez Gene: 1628
Ensembl: ENSG00000105516
UCSC: uc002pjx.4
No. of Studies 3 (Positive: 0; Negative: 3; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 3)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Soria, V.,2010 SNP: rs386551 No significant associations of DBP gene were found in BPD patients. Negative Comment on Study
Mansour, H. A.,2009 Gene-based tests:X<sup>2</sup>=2.109, P-value = 0.273 in recessive model, X<sup>2</sup>=1.578, P-value = 0.377 in dominant model, X<sup>2</sup>=0.703, P-value = 0.632 in additive model in BPI. No significant association was observed using neither single SNP-based analyses nor gene-based tests in BPI. Negative Comment on Study
Nievergelt, C. M., 2006 Single SNP TDT analyses showed no evidence for association to BPAD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 8)

GO terms by PBA (count: 1)

GO terms by database search (count: 7)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 4)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 1)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr19:48630030..48637438 View in gBrowse
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