BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Study Report

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Basic Info

Reference	Zhang, C., 2016 PMID: 26731438
Citation	Zhang, C., et al. (2016). "A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese." Transl Psychiatry 6: e701.
Disease Type	Schizophrenia & Bipolar Disorder
Study Design	case-control
Study Type	Candidate-gene association study, meta-analysis
Sample Size	In stage 1: 632 patients with schizophrenia, 654 patients with BD and 684 healthy controls; In stage 2: 522 schizophrenia patients and 547 normal subjects.
SNP/Region/Marker Size	5 SNPs
Predominant Ethnicity	Han Chinese
Population	Shanghai and Hangzhou

Detail Info

SNPs reported by this study for BD (count: 6)

SNP	Related Gene(s)	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
rs6534078	NDST3	A/G		P-value=0.16,Â OR=0.88, 95%CI=0.74-1.05	In a comparison between the BD and control groups, no signif...... In a comparison between the BD and control groups, no significant difference was observed in individual SNP marker genotypes or allele distributions. More...	Negative
rs11098403	NDST3	G/A		P-value=0.03,Â OR=0.80, 95%CI=0.65-0.98	In a comparison between the BD and control groups, no signif...... In a comparison between the BD and control groups, no significant difference was observed in individual SNP marker genotypes or allele distributions. More...	Negative
rs12642204	NDST3	T/C		P-value=0.09,Â OR=0.86, 95%CI=0.72-1.02	In a comparison between the BD and control groups, no signif...... In a comparison between the BD and control groups, no significant difference was observed in individual SNP marker genotypes or allele distributions. More...	Negative
rs2389519	NDST3	T/G		P-value=0.08,Â OR=0.85, 95%CI=0.70-1.02	In a comparison between the BD and control groups, no signif...... In a comparison between the BD and control groups, no significant difference was observed in individual SNP marker genotypes or allele distributions. More...	Negative
rs4327555	NDST3	T/A		P-value=0.28,Â OR=0.92, 95%CI=0.79-1.07	In a comparison between the BD and control groups, no signif...... In a comparison between the BD and control groups, no significant difference was observed in individual SNP marker genotypes or allele distributions. More...	Negative
rs631271	NDST3	A/G		P-value=0.85,Â OR=0.98, 95%CI=0.82-1.18	In a comparison between the BD and control groups, no signif...... In a comparison between the BD and control groups, no significant difference was observed in individual SNP marker genotypes or allele distributions. More...	Negative