SNP Report

Basic Info

Name	rs8192624 dbSNP Ensembl
Location	chr6:132571114 - 132571114(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.0571086
Functional Annotation	missense_variant. Polyphen Annotation: benign(ENST00000275198) SIFT Annotation: tolerated(ENST00000275198)
Consequence to Transcript	missense_variant(ENST00000275198)
No. of Studies	2 (Positive: 2; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Abou Jamra, R.,2005(b)	G/A		In family base study: TDT P-value = 0.014; in case-control s...... In family base study: TDT P-value = 0.014; in case-control study: ARMITAGES TREND TEST P-values (odds ratio, 95% CI)=0.024 (1.63, 1.03-2.55). More...	Significant association was observed in both familiy-base st...... Significant association was observed in both familiy-base study and case-control study. More...	Positive
Liu, C., 2007	A/G		TDT P-value = 0.11 in CNG+NIMH waves I+2, TDT P-value = 0.02...... TDT P-value = 0.11 in CNG+NIMH waves I+2, TDT P-value = 0.022 in NIMH waves 3+4 + CHIP, TDT P-value = 0.0048 in Entire sample More...	SNP rs8192624 showed nominally significant association in th...... SNP rs8192624 showed nominally significant association in the second set of samples, as well as in the combined samples; we observed nominally significant association between minor allele (A) and BD More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TAAR6	trace amine associated receptor 6	6q23.1	5(4/1/0)

SNPs in LD with rs8192624 (count: 0) View in gBrowse (chr6:132571114..132571114 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)