BDgene

SNP Report

Basic Info
Name rs683395 dbSNP Ensembl
Location chr3:183152030 - 183152030(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele G
Minor Allele Frequence 0.129593
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000470251, ENST00000476015); intron_variant(ENST00000265598, ENST00000466939)
No. of Studies 3 (Positive: 0; Negative: 1; Trend: 2)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Ollila, H. M.,2009 A/G FBAT: P-value = 0.705905 FBAT: P-value = 0.705905 No significant association was observed No significant association was observed Negative
The Wellcome Trust Case Control Consortium, 2007 G Genotypic P-value = 5.11E-06; Heterozygote OR (95%CI)=1.47 ...... Genotypic P-value = 5.11E-06; Heterozygote OR (95%CI)=1.47 (1.26-1.71); Homozygote OR (95%CI)=1.30 (0.69-2.46) More... showing moderate evidence of association with BD showing moderate evidence of association with BD Trend
Jiang, Y.,2011 Non-weighted test under H0: P-value(additive)=0.0000023, P-v...... Non-weighted test under H0: P-value(additive)=0.0000023, P-value(dominant)=0.000000857, P-value(recessive)=0.544; weighted test under H'0: P-value(additive)=0.0000229, P-value(dominant)=0.00000388, P-value(recessive)=0.472; logistic regression: P-value(additive)=0.00000274, P-value(dominant)=0.00000121, P-value(recessive)=0.456 More... Suggestive association was found. Suggestive association was found. Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
LAMP3 lysosomal-associated membrane protein 3 3q26.3-q27 1(1/0/0)

SNPs in LD with rs683395 (count: 5) View in gBrowse (chr3:183152030..183162323 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)