SNP Report

Basic Info
Name rs385440 dbSNP Ensembl
Location chr22:18913577 - 18913577(1)
Variant Alleles A/G
Minor Allele A
Minor Allele Frequence 0.158147
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000483718); downstream_gene_variant(ENST00000331444, ENST00000413981, ENST00000427407, ENST00000436645, ENST00000477156, ENST00000480608, ENST00000609229); intron_variant(ENST00000313755, ENST00000334029, ENST00000357068, ENST00000420436, ENST00000429300, ENST00000482858, ENST00000491604, ENST00000610940); NMD_transcript_variant(ENST00000483718); non_coding_transcript_variant(ENST00000313755, ENST00000429300, ENST00000482858, ENST00000491604)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Prata, D. P., 2006 no P-value no P-value A chi-square analysis showed no genotype-wise or allele-wise...... A chi-square analysis showed no genotype-wise or allele-wise association for any individual SNP. More... Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
DGCR6 DiGeorge syndrome critical region gene 6 22q11.21 1(0/1/0)
PRODH proline dehydrogenase (oxidase) 1 22q11.2 4(0/4/0)

SNPs in LD with rs385440 (count: 8) View in gBrowse (chr22:18913577..18917604 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 8)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)