BDgene

SNP Report

Basic Info
Name rs3761218 dbSNP Ensembl
Location chr20:3795528 - 3795528(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.342053
Functional Annotation intron_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000344256, ENST00000379598); upstream_gene_variant(ENST00000245960, ENST00000340833, ENST00000439880, ENST00000467519)
No. of Studies 3 (Positive: 1; Negative: 1; Trend: 1)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
The Wellcome Trust Case Control Consortium, 2007 T/C T Genotypic P-value = 6.71E-06; Heterozygote OR (95%CI)=0.97 ...... Genotypic P-value = 6.71E-06; Heterozygote OR (95%CI)=0.97 (0.81-1.15); Homozygote OR (95%CI)=1.31 (1.09-1.57) More... showing moderate evidence of association with BD showing moderate evidence of association with BD Trend
Ollila, H. M.,2009 T/C FBAT: P-value = 0.340967 FBAT: P-value = 0.340967 No significant association was observed No significant association was observed Negative
Jiang, Y.,2011 Non-weighted test under H0: P-value(additive)=0.0000444, P-v...... Non-weighted test under H0: P-value(additive)=0.0000444, P-value(dominant)=0.00000113, P-value(recessive)=0.214; weighted test under H'0: P-value(additive)=0.00053, P-value(dominant)=0.00000327, P-value(recessive)=0.0713; logistic regression: P-value(additive)=0.0000116, P-value(dominant)=0.000000216, P-value(recessive)=0.173 More... Significant associations were found . Significant associations were found . Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CDC25B cell division cycle 25B 20p13 1(0/1/0)

SNPs in LD with rs3761218 (count: 4) View in gBrowse (chr20:3775950..3796321 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)