SNP Report

Basic Info
Name rs303810 dbSNP Ensembl
Location chr12:51769464 - 51769464(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele A
Minor Allele Frequence 0.321486
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000550891); intron_variant(ENST00000354534, ENST00000355133, ENST00000545061, ENST00000599343, ENST00000627620, ENST00000627665, ENST00000636945, ENST00000637709); NMD_transcript_variant(ENST00000636945, ENST00000637709); non_coding_transcript_variant(ENST00000627665); upstream_gene_variant(ENST00000548086, ENST00000636458)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Wang, Y., 2008 C/T Allelic P-value = 0.0047, permutated P-value = 0.0164; geno...... Allelic P-value = 0.0047, permutated P-value = 0.0164; genotypic P-value = 0.0051 More... This SNP showed statistically significant differences betwee...... This SNP showed statistically significant differences between bipolar patients and controls in both allele and genotype distribution. only rs303810 was still significant in allele distribution when permutated 100, 000 times on Haploview 4.0RC1. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SCN8A sodium channel, voltage gated, type VIII alpha subunit 12q13.1 1(1/0/0)

SNPs in LD with rs303810 (count: 18) View in gBrowse (chr12:51705369..51770005 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 18)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)