BDgene

SNP Report

Basic Info
Name rs1927914 dbSNP Ensembl
Location chr9:117702447 - 117702447(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele G
Minor Allele Frequence 0.490415
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000355622, ENST00000394487, ENST00000472304)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Oliveira, J., 2013 A/G rs1927914 AA vs. AG + GG: 48% vs. 37%, P-value=0.008, pc=0.0...... rs1927914 AA vs. AG + GG: 48% vs. 37%, P-value=0.008, pc=0.02; OR=1.56, CI95%=1.11-2.20 More... The analysis of TLR-4 genotype distribution revealed that th...... The analysis of TLR-4 genotype distribution revealed that the homozygous state for TLR-4 rs1927914 A was significantly more prevalent in BD patients than in HC. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TLR4 toll-like receptor 4 9q33.1 1(1/0/0)

SNPs in LD with rs1927914 (count: 18) View in gBrowse (chr9:117665121..117711921 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 18)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)