SNP Report

Basic Info

Name	rs1927914 dbSNP Ensembl
Location	chr9:117702447 - 117702447(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.490415
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000355622, ENST00000394487, ENST00000472304)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Oliveira, J., 2013	A/G		rs1927914 AA vs. AG + GG: 48% vs. 37%, P-value=0.008, pc=0.0...... rs1927914 AA vs. AG + GG: 48% vs. 37%, P-value=0.008, pc=0.02; OR=1.56, CI95%=1.11-2.20 More...	The analysis of TLR-4 genotype distribution revealed that th...... The analysis of TLR-4 genotype distribution revealed that the homozygous state for TLR-4 rs1927914 A was significantly more prevalent in BD patients than in HC. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TLR4	toll-like receptor 4	9q33.1	1(1/0/0)

SNPs in LD with rs1927914 (count: 18) View in gBrowse (chr9:117665121..117711921 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs1360092	downstream_gene_variant	0.952[CEU]
rs10116253	upstream_gene_variant	0.813[CEU]
rs1928298	downstream_gene_variant	0.952[CEU]; 0.974[TSI]
rs1360093	upstream_gene_variant	0.952[CEU]
rs1928297	downstream_gene_variant	0.813[CEU]
rs2737190	upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs2149356	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.951[CEU]
rs3904153	downstream_gene_variant	0.942[CEU]
rs4837495	upstream_gene_variant	0.904[CEU]
rs1854448		0.86[CEU]
rs1360094	upstream_gene_variant	0.908[CEU]; 1.0[TSI]
rs1927911	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.813[CEU]
rs1854447		0.86[CEU]
rs1329061		0.95[CEU]; 0.974[TSI]
rs4837497		1.0[CEU]; 1.0[TSI]
rs10818068	downstream_gene_variant	0.95[CEU]
rs4837496	upstream_gene_variant	0.813[CEU]
rs7873159	upstream_gene_variant	0.813[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)