SNP Report

Basic Info

Name	rs11657992 dbSNP Ensembl
Location	chrCHR_HSCHR17_2_CTG5:45855165 - 45855165(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.0183706
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant; non_coding_transcript_exon_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000579244, ENST00000579599, ENST00000581125); intron_variant(ENST00000634876); non_coding_transcript_variant(ENST00000634876); upstream_gene_variant(ENST00000329196, ENST00000628274, ENST00000630938); non_coding_transcript_exon_variant(ENST00000629948, ENST00000629948, ENST00000610319, ENST00000632082, ENST00000633458, ENST00000633517, ENST00000633517, ENST00000621383)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	T/C		Single SNP analyses: Permuted P-value = 0.7279, Odds Ratio=0...... Single SNP analyses: Permuted P-value = 0.7279, Odds Ratio=0.9363 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAPT-AS1	MAPT antisense RNA 1	17q21.31	Mapped by Literature SNP
SPPL2C	signal peptide peptidase like 2C	17q21.31	Mapped by Literature SNP
CRHR1	corticotropin releasing hormone receptor 1	17q21.31	4(2/2/0)

SNPs in LD with rs11657992 (count: 1) View in gBrowse (chrCHR_HSCHR17_2_CTG5:45763787..45855165 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs17335035		intron_variant; non_coding_transcript_variant	0.828[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)