BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	10p12
Chromosome Position	chr10:17300000-29300000
No. of Studies (Positive/Negative/Trend)	3(0/1/2)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Lambert, D.,2005	D10S197, D10S548	Linkage analysis: For marker D10S197, Two point LOD score = ...... Linkage analysis: For marker D10S197, Two point LOD score = 1.55(narrow), 2.45(intermediate), 3.18(broad); For marker D10S548, Multipoint MLS = 1.12(narrow), 0.62(intermediate), 0.46(broad); Two point LOD score = 0.73(narrow), 0.04(intermediate), 0.03(broad); More...	Suggestive linkage was found in this region at D10S197. Suggestive linkage was found in this region at D10S197.	Trend
Bennett, P.,2002	D10S548	Linkage analysis: LOD = 0.36, Multipoint MLS(narrow model) =...... Linkage analysis: LOD = 0.36, Multipoint MLS(narrow model) = 0.96 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
McInnis, M. G.,2003(a)	D10S1423	Linkage analysis: model H, Conditional NPL = 2.8, P-value = ...... Linkage analysis: model H, Conditional NPL = 2.8, P-value = 0.001 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	10p13-p11.2	1(0/1/0)
PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	10p12.2	4(1/3/0)
CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10p12	3(2/1/0)

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Region: chr10:17300000..29300000 View in gBrowse