Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	XXYLT1
Previous Symbol	C3orf21
Symbol Alias	FLJ35155
Approved Name	xyloside xylosyltransferase 1
Previous Name	chromosome 3 open reading frame 21
Location	3q29
Position	chr3:195068279-195271167, -1
External Links	HGNC: 26639 Entrez Gene: 152002 Ensembl: ENSG00000173950 UCSC: uc003fum.4
No. of Studies	2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 2)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Schosser, A.,2011	SNP: rs4677666	No significant association was observed.	Negative	Comment on Study
Xu, W., 2014	SNP: rs2410806	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005789	endoplasmic reticulum membrane	cellular component	IEA	52
GO:0008152	metabolic process	biological process	IEA	50
GO:0016763	transferase activity, transferring pentosyl groups	molecular function	IEA	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 3)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs2410806	chr3:195199226 - 195199226(1)	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1(0/1/0)
rs4677666	chr3:195266840 - 195266840(1)	intron_variant; NMD_transcript_variant	1(0/1/0)

rs_ID	Literature-origin SNPs with LD	Location	Functional Annotation
rs10933704		chr3:195268144 - 195268144(1)	intron_variant; NMD_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 3	chr3:0-198295559	2 (0/2/0)
3q29	chr3:192600000-198295559	2 (1/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr3:195068279..195271167 View in gBrowse