Gene Report

Basic Info
Approved Symbol TRIB1
Symbol Alias C8FW, GIG2, TRB1
Approved Name tribbles pseudokinase 1
Previous Name tribbles homolog 1 (Drosophila)
Location 8q24.13
Position chr8:125430321-125438405, 1
External Links HGNC: 16891
Entrez Gene: 10221
Ensembl: ENSG00000173334
UCSC: uc003yrx.4
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gonzalez, S., 2014 SNP: rs10956248, rs921720, rs2124036, rs1488019
Other variant: TRIB1_Chr8:126514759
It showed nominal evidence for association with BD. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 19)

GO terms by PBA (count: 2)

GO terms by database search (count: 17)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 4)

Literature-origin SNPs (count: 4)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr8:125430321..125438405 View in gBrowse
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