Gene Report

Basic Info
Approved Symbol SPRED1
Symbol Alias FLJ33903, PPP1R147
Approved Name sprouty-related, EVH1 domain containing 1
Name Alias protein phosphatase 1, regulatory subunit 147
Location 15q14
Position chr15:38252326-38357249, 1
External Links HGNC: 20249
Entrez Gene: 161742
Ensembl: ENSG00000166068
UCSC: uc001zka.4
No. of Studies 2 (Positive: 0; Negative: 1; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Sklar, P.,2011 SNP: rs16966413 No significant association was observed. Negative Comment on Study
Green, E. K.,2012 SNP: rs16966413 BD ImmunoChip:P-value = 0.015,OR = 0.824;ImmunoChip, PGC-BD combined data:P-balue = 0.00000593,OR = 0.872 Suggestive association was found. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 14)

GO terms by PBA (count: 1)

GO terms by database search (count: 13)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr15:38252326..38357249 View in gBrowse
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