SNP Report

Basic Info

Name	rs16966413 dbSNP Ensembl
Location	chr15:38187698 - 38187698(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.105232
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000561161, ENST00000561320); non_coding_transcript_variant(ENST00000561161, ENST00000561320)
No. of Studies	2 (Positive: 0; Negative: 1; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Sklar, P.,2011	A/G		Primary GWAS P-value(GC)=0.0000474, OR=0.84; replication P-v...... Primary GWAS P-value(GC)=0.0000474, OR=0.84; replication P-value(1-sided)=0.16, OR=0.95; Combined GWAS and replication P-value(GC)=0.0000997, OR=0.88 More...	No significant association was observed. No significant association was observed.	Negative
Green, E. K.,2012	A/G		BD ImmunoChip:P-value = 0.015,OR = 0.824;ImmunoChip, PGC-BD ...... BD ImmunoChip:P-value = 0.015,OR = 0.824;ImmunoChip, PGC-BD combined data:P-balue = 0.00000593,OR = 0.872 More...	Suggestive association was found. Suggestive association was found.	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SPRED1	sprouty-related, EVH1 domain containing 1	15q14	2(0/1/1)

SNPs in LD with rs16966413 (count: 10) View in gBrowse (chr15:38107220..38227382 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs17640033		0.913[CEU]
rs16966460	intron_variant; non_coding_transcript_variant	0.833[CEU]
rs8032887	intron_variant; non_coding_transcript_variant	0.82[CEU]
rs17559713		0.919[CEU]
rs16966471	upstream_gene_variant	0.82[CEU]
rs4923776	intron_variant; non_coding_transcript_variant	0.833[CEU]
rs16966423	intron_variant; non_coding_transcript_variant	0.82[CEU]
rs8027757		0.913[CEU]
rs7176853		0.913[CEU]
rs16966249		0.913[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)