BDgene

SNP Report

Basic Info
Name rs16966413 dbSNP Ensembl
Location chr15:38187698 - 38187698(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.105232
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000561161, ENST00000561320); non_coding_transcript_variant(ENST00000561161, ENST00000561320)
No. of Studies 2 (Positive: 0; Negative: 1; Trend: 1)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Sklar, P.,2011 A/G Primary GWAS P-value(GC)=0.0000474, OR=0.84; replication P-v...... Primary GWAS P-value(GC)=0.0000474, OR=0.84; replication P-value(1-sided)=0.16, OR=0.95; Combined GWAS and replication P-value(GC)=0.0000997, OR=0.88 More... No significant association was observed. No significant association was observed. Negative
Green, E. K.,2012 A/G BD ImmunoChip:P-value = 0.015,OR = 0.824;ImmunoChip, PGC-BD ...... BD ImmunoChip:P-value = 0.015,OR = 0.824;ImmunoChip, PGC-BD combined data:P-balue = 0.00000593,OR = 0.872 More... Suggestive association was found. Suggestive association was found. Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SPRED1 sprouty-related, EVH1 domain containing 1 15q14 2(0/1/1)

SNPs in LD with rs16966413 (count: 10) View in gBrowse (chr15:38107220..38227382 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)