Gene Report

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Basic Info

Approved Symbol	SLC39A3
Symbol Alias	ZIP3
Approved Name	solute carrier family 39 (zinc transporter), member 3
Location	19p13.3
Position	chr19:2732204-2740152, -1
External Links	HGNC: 17128 Entrez Gene: 29985 Ensembl: ENSG00000141873 UCSC: uc002lwg.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Ollila, H. M.,2009	SNP: rs4806874	It showed no evidence for association with BPI in our study.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219
GO:0005886	plasma membrane	cellular component	TAS	360

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0071577	zinc II ion transmembrane transport	biological process	IEA	2
GO:0055085	transmembrane transport	biological process	TAS	77
GO:0005385	zinc ion transmembrane transporter activity	molecular function	IEA	2

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 5)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs4806874	chr19:2738354 - 2738354(1)	intron_variant; non_coding_transcript_variant	2(0/1/1)

rs_ID	Location	Functional Annotation
rs2302490	chr19:2740231 - 2740231(1)	upstream_gene_variant
rs10415622	chr19:2739698 - 2739698(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs10407667	chr19:2731529 - 2731529(1)	downstream_gene_variant; intron_variant; upstream_gene_variant
rs759071	chr19:2728579 - 2728579(1)	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
19p13-q13	chr19:0-58617616	1 (0/1/0)
Chr 19	chr19:0-58617616	2 (0/2/0)
19q13.3	chr19:0-6900000	1 (0/1/0)
19p13	chr19:0-19900000	2 (0/1/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr19:2732204..2740152 View in gBrowse