BDgene

Gene Report

Basic Info
Approved Symbol PNOC
Symbol Alias PPNOC
Approved Name prepronociceptin
Name Alias nocistatin
Location 8p21
Position chr8:28316986-28343355, 1
External Links HGNC: 9163
Entrez Gene: 5368
Ensembl: ENSG00000168081
UCSC: uc003xgp.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 7 SNP typed, Median D'=1, Median r<sup>2</sup> =0.09, 1 LD blocks, 0.67 block coverage, there exists SNP or haplotype nominal P-value > 0.01 and <0.05 in SZ and all SNP or haplotype P-value > 0.05 in BP.. This gene is suggestive to SZ/SZA , not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 8)

GO terms by PBA (count: 1)

GO terms by database search (count: 7)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 3)


Gene relationship with MDD

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Region: chr8:28316986..28343355 View in gBrowse
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