Gene Report

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Basic Info

Approved Symbol	MFSD11
Symbol Alias	FLJ22196, FLJ20226
Approved Name	major facilitator superfamily domain containing 11
Location	17q25.1
Position	chr17:76735865-76781449, 1
External Links	HGNC: 25458 Entrez Gene: 79157 Ensembl: ENSG00000092931 UCSC: uc002jte.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs9897202	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005575	cellular_component	cellular component	ND	19
GO:0003674	molecular_function	molecular function	ND	24
GO:0008150	biological_process	biological process	ND	24

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 8)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs9897202	chr17:76739260 - 76739260(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs4789351	chr17:76732856 - 76732856(1)	5_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs2058215	chr17:76732000 - 76732000(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs237054	chr17:76738241 - 76738241(1)	5_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant
rs237059	chr17:76734761 - 76734761(1)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant
rs116719	chr17:76754249 - 76754249(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant
rs237053	chr17:76738516 - 76738516(1)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant
rs12451142	chr17:76756425 - 76756425(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
17q25	chr17:72900000-83257441	1 (0/0/1)
17q11-25	chr17:25100000-83257441	1 (1/0/0)
Chr 17	chr17:0-83257441	3 (0/3/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr17:76735865..76781449 View in gBrowse