BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	PLA2 1-8 allele
Type	duplication
Related Gene	PLA2G1B
No. of Study	2 (Positive: 0; Negative 2; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Variant related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Dikeos, D. G., 2006	1-8 allele		allelic P-value = 0.15 (NS), X²=10.685, df=7; P-value = 0.13 (NS), X²=8.513, df=5 after pooling rare alleles (alleles 1, 5, and 8); genotypic P-value = 0.40, X²=8.337, df=8	Allele percentages did not differ substantially between pati..... More Allele percentages did not differ substantially between patients and controls. Genotypic association was not observed for genotypes with frequencies greater than 3%. Less	Negative
Jacobsen, N.,1996	1-8 allele		chi square test:allele P-value=0.09	No significant differences were found in bipolar groups.	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)