BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Study Report

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Basic Info

Reference	Jacobsen, N.,1996 PMID: 9149325
Citation	Jacobsen, N., J. Daniels, et al. (1996). "Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23-q24.1." Psychiatr Genet 6(4): 195-199.
Disease Type	Bipolar Disorder
Study Design	case-control
Study Type	Candidate-gene association study
Sample Size	127 bipolar patients and 223 controls
SNP/Region/Marker Size	1 variant
Predominant Ethnicity	Caucasian
Population	British
Gender	81 females in BD patients and 44 females in controls
Age Group	Adults : Mean age(SD)(year):44(11) for BD patients and 51(17) for controls

Detail Info

Other variants reported by this study for BD (count: 1)

Variant Name	Related Gene	Type	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
PLA2 1-8 allele	PLA2G1B	duplication	1-8 allele		chi square test:allele P-value=0.09	No significant differences were found in bipolar groups. No significant differences were found in bipolar groups.	Negative

Genes reported by this study for BD (count: 1)