SNP Report

Basic Info

Name	rs7917746 dbSNP Ensembl
Location	chrCHR_HG2191_PATCH:74907902 - 74907902(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.363219
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000287239, ENST00000372711, ENST00000372714, ENST00000372724, ENST00000372725, ENST00000628038, ENST00000628523, ENST00000629233, ENST00000629879, ENST00000630001)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kuo, P. H., 2014			P-value=0.03282,Â OR=0.7, 95%CI=0.6-0.98 for the second stag...... P-value=0.03282,Â OR=0.7, 95%CI=0.6-0.98 for the second stage More...	The marker is identified to be associated with bipolar disor...... The marker is identified to be associated with bipolar disorder in the fine-mapping stage with P-value less than 0.05. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
KAT6B	K(lysine) acetyltransferase 6B	10q22.2	1(1/0/0)

SNPs in LD with rs7917746 (count: 21) View in gBrowse (chrCHR_HG2191_PATCH:74885296..75036856 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2395125	intron_variant	0.95[CHB]; 1.0[JPT]
rs1551067	downstream_gene_variant; intron_variant; upstream_gene_variant	0.808[CHB]
rs2395121	intron_variant	0.95[CHB]; 1.0[JPT]
rs12260609	intron_variant	0.804[JPT]
rs10824242	intron_variant	0.804[JPT]
rs1868628	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.808[CHB]
rs2278804	intron_variant; non_coding_transcript_variant	0.904[CHB]
rs4746250	intron_variant; non_coding_transcript_variant	0.808[CHB]
rs11001252	downstream_gene_variant	0.808[CHB]
rs10824245	intron_variant	0.95[CHB]; 0.801[CHD]; 1.0[JPT]
rs7092435	intron_variant	0.95[CHB]; 1.0[JPT]
rs2395124	intron_variant	0.949[CHB]; 0.801[CHD]; 1.0[JPT]
rs7072392	intron_variant	0.95[CHB]; 1.0[JPT]
rs10824251	intron_variant	0.942[CHB]
rs4745760	intron_variant	0.95[CHB]; 1.0[JPT]
rs7072471	intron_variant	0.949[CHB]; 1.0[JPT]
rs3213967	intron_variant	0.904[CHB]
rs2278803	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.904[CHB]
rs4746247	intron_variant	0.95[CHB]; 1.0[JPT]
rs6480764	intron_variant	0.95[CHB]; 1.0[JPT]
rs1880690	intron_variant	0.95[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)