SNP Report

Basic Info

Name	rs7461611 dbSNP Ensembl
Location	chr8:132036372 - 132036372(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.267772
Functional Annotation	intron_variant; splice_region_variant; synonymous_variant.
Consequence to Transcript	intron_variant(ENST00000254627); splice_region_variant(ENST00000262283); synonymous_variant(ENST00000262283)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	A/G		P-value=5.9E-05 P-value=5.9E-05	Top 132 SNPs (showing suggestive association to BD in our CA...... Top 132 SNPs (showing suggestive association to BD in our CAMH family cohort: p<0.0001). More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
OC90	otoconin 90	8q24.22	1(0/1/0)

SNPs in LD with rs7461611 (count: 12) View in gBrowse (chr8:132026910..132041071 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs7386783	missense_variant	0.911[CEU]; 0.844[TSI]
rs7465374	intron_variant	1.0[CEU]; 1.0[TSI]
rs7465349	intron_variant	1.0[CEU]
rs6992506	intron_variant	1.0[CEU]; 1.0[TSI]
rs6415547	intron_variant	1.0[CEU]
rs7386782	missense_variant	0.911[CEU]; 0.844[TSI]
rs1995315	intron_variant	1.0[CEU]
rs7834841	intron_variant	1.0[CEU]; 1.0[TSI]
rs6471027	intron_variant	1.0[CEU]; 1.0[TSI]
rs7387407	intron_variant	0.942[CEU]
rs7840213	intron_variant	0.955[CEU]; 0.971[TSI]
rs871960	intron_variant	0.911[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)