SNP Report

Basic Info

Name	rs694539 dbSNP Ensembl
Location	chr11:114262697 - 114262697(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.255591
Functional Annotation	intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000535185, ENST00000535401, ENST00000544925); non_coding_transcript_variant(ENST00000535185, ENST00000544925); upstream_gene_variant(ENST00000541090)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Sazci, A., 2013	G/A		P-value=0.001, X²=13.382; P-value=0.001, X^2<...... P-value=0.001, X²=13.382; P-value=0.001, X²=11.981, OR; 95% CI=0.414 (0.250-0.686) for GG genotype; , P-value=0.003, X²=8.777, OR; 95% CI=2.141 (1.288-3.559) for GA genotype; P-value=0.067, X²=3.359, OR; 95% CI=4.374 (0.787-24.313) for AA genotype; P-value=0.067, X²=3.359, OR; 95% CI=0.229 (0.041-1.271) for G allele; P-value=0.001, X²=11.981, OR; 95% CI=2.414 (1.457-4.000) for A allele More...	rs694539 variant of NNMT gene is associated with bipolar dis...... rs694539 variant of NNMT gene is associated with bipolar disorders; Although the individuals with GG genotype showed protection towards bipolar disorders, the individuals with GA genotype had a 2.141-fold increased risk for bipolar disorders; Moreover the A allele showed statistically significant association with bipolar disorders. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NNMT	nicotinamide N-methyltransferase	11q23.1	1(1/0/0)

SNPs in LD with rs694539 (count: 0) View in gBrowse (chr11:114262697..114262697 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)