SNP Report

Basic Info

Name	rs6495309 dbSNP Ensembl
Location	chr15:78622903 - 78622903(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.370008
Functional Annotation	downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000261751, ENST00000412074); upstream_gene_variant(ENST00000326828, ENST00000348639, ENST00000559080, ENST00000559120, ENST00000559658, ENST00000559941, ENST00000561128)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2007	G/A		TDT P-value = 0.2 of Allelic Association With Bipolar Disord...... TDT P-value = 0.2 of Allelic Association With Bipolar Disorder in the Combined Sample More...		Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHRNA3	cholinergic receptor, nicotinic, alpha 3 (neuronal)	15q24	3(1/2/0)
CHRNB4	cholinergic receptor, nicotinic, beta 4 (neuronal)	15q24	2(1/1/0)

SNPs in LD with rs6495309 (count: 11) View in gBrowse (chr15:78571130..78637030 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4887069	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.824[CEU]
rs569207	intron_variant; upstream_gene_variant	0.878[CEU]; 0.847[TSI]
rs8042374	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.94[CEU]; 0.903[TSI]
rs6495308	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.94[CEU]; 0.903[TSI]
rs667282	intron_variant	0.878[CEU]; 0.847[TSI]
rs12910984	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.94[CEU]; 0.899[TSI]
rs518425	downstream_gene_variant; intron_variant; upstream_gene_variant	0.83[CEU]
rs12441998	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.833[TSI]
rs938682	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.94[CEU]; 0.903[TSI]
rs8042059	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.94[CEU]; 0.903[TSI]
rs7177514	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.94[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)