BDgene

SNP Report

Basic Info
Name rs6458307 dbSNP Ensembl
Location chr6:42763377 - 42763377(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele T
Minor Allele Frequence 0.365216
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000614467)
No. of Studies 3 (Positive: 0; Negative: 1; Trend: 2)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Ollila, H. M.,2009 C/T FBAT: P-value = 0.582353 FBAT: P-value = 0.582353 No significant association was observed No significant association was observed Negative
Jiang, Y.,2011 Non-weighted test under H0: P-value(additive)=0.343, P-value...... Non-weighted test under H0: P-value(additive)=0.343, P-value(dominant)=0.211, P-value(recessive)=0.0000282; weighted test under H'0: P-value(additive)=0.167, P-value(dominant)=0.26, P-value(recessive)=0.00000787; logistic regression: P-value(additive)=0.284, P-value(dominant)=0.244, P-value(recessive)=0.000019 More... Suggestive association was found. Suggestive association was found. Trend
The Wellcome Trust Case Control Consortium, 2007 T Genotypic P-value = 4.35E-06; Heterozygote OR (95%CI)=0.84 ...... Genotypic P-value = 4.35E-06; Heterozygote OR (95%CI)=0.84 (0.75-0.96); Homozygote OR (95%CI)=1.39 (1.13-1.69) More... showing moderate evidence of association with BD showing moderate evidence of association with BD Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GLTSCR1L GLTSCR1-like 6p21.1 Mapped by Literature SNP

SNPs in LD with rs6458307 (count: 1) View in gBrowse (chr6:42758611..42763377 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)