SNP Report

Basic Info

Name	rs4887376 dbSNP Ensembl
Location	chr15:88175992 - 88175992(1)
Variant Alleles	T/G
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.445088
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000317501, ENST00000355254, ENST00000357724, ENST00000360948, ENST00000394480, ENST00000540489, ENST00000542733, ENST00000557856, ENST00000558676, ENST00000559188, ENST00000626019, ENST00000629765)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Athanasiu, L.,2011	G/T		Allelic association: OR=1.275, P-value = 5.75E-02, P-value(t...... Allelic association: OR=1.275, P-value = 5.75E-02, P-value(trend)=6.28E-02 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q24-q25	2(2/0/0)

SNPs in LD with rs4887376 (count: 2) View in gBrowse (chr15:88141224..88193744 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs1991287		downstream_gene_variant; intron_variant; upstream_gene_variant	0.841[CEU]
rs11629691		intron_variant	0.876[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)