BDgene

SNP Report

Basic Info
Name rs452223 dbSNP Ensembl
Location chr5:157184482 - 157184482(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.263778
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000422843, ENST00000517779, ENST00000519402, ENST00000520555, ENST00000521769, ENST00000522616, LRG_189t1); NMD_transcript_variant(ENST00000517779); non_coding_transcript_variant(ENST00000519402, ENST00000520555, ENST00000522616)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kerner, B.,2009 G/A FBAT: Wave 1: Z-score=2.4, P-value = 0.01; Waves 1-4: Z-scor...... FBAT: Wave 1: Z-score=2.4, P-value = 0.01; Waves 1-4: Z-score=3.1, P-value = 0.002 More... Significant association was observed in Wave 1 and Wave 1-4. Significant association was observed in Wave 1 and Wave 1-4. Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ITK IL2-inducible T-cell kinase 5q31-q32 1(1/0/0)

SNPs in LD with rs452223 (count: 0) View in gBrowse (chr5:157184482..157184482 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)