SNP Report

Basic Info

Name	rs452223 dbSNP Ensembl
Location	chr5:157184482 - 157184482(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.263778
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000422843, ENST00000517779, ENST00000519402, ENST00000520555, ENST00000521769, ENST00000522616, LRG_189t1); NMD_transcript_variant(ENST00000517779); non_coding_transcript_variant(ENST00000519402, ENST00000520555, ENST00000522616)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kerner, B.,2009	G/A		FBAT: Wave 1: Z-score=2.4, P-value = 0.01; Waves 1-4: Z-scor...... FBAT: Wave 1: Z-score=2.4, P-value = 0.01; Waves 1-4: Z-score=3.1, P-value = 0.002 More...	Significant association was observed in Wave 1 and Wave 1-4. Significant association was observed in Wave 1 and Wave 1-4.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ITK	IL2-inducible T-cell kinase	5q31-q32	1(1/0/0)

SNPs in LD with rs452223 (count: 0) View in gBrowse (chr5:157184482..157184482 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)