SNP Report

Basic Info

Name	rs3798346 dbSNP Ensembl
Location	chr6:35594863 - 35594863(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.120807
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000357266, ENST00000536438, ENST00000539068, ENST00000542713)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Willour, V. L.,2009	A/G		FBAT: Additive model: major allele P-value = 0.137, minor al...... FBAT: Additive model: major allele P-value = 0.137, minor allele P-value = 0.137; Dominant model: major allele P-value = 0.177, minor allele P-value = 0.285; Genotypic association: TDT P-value = 0.35 More...	No significant association was observed No significant association was observed	Negative
Ceulemans, S.,2011	G/A		Single SNP analyses: Permuted P-value = 0.3615, Odds Ratio=0...... Single SNP analyses: Permuted P-value = 0.3615, Odds Ratio=0.8876 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
FKBP5	FK506 binding protein 5	6p21.31	5(1/4/0)

SNPs in LD with rs3798346 (count: 4) View in gBrowse (chr6:35554368..35703874 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs9470056	upstream_gene_variant	0.952[CEU]; 0.835[TSI]
rs9470059	downstream_gene_variant	0.952[CEU]
rs10456432	intron_variant	0.858[TSI]
rs6924087		0.952[CEU]; 0.835[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)