SNP Report

Basic Info

Name	rs275645 dbSNP Ensembl
Location	chr3:148746667 - 148746667(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.498802
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000349243, ENST00000402260, ENST00000404754, ENST00000418473, ENST00000461609, ENST00000474935, ENST00000475347, ENST00000497524)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Gratacos, M.,2009			Single SNP association: In control and bipolar disorder samp...... Single SNP association: In control and bipolar disorder samples: Recessive Model, P-value = 0.0136(corrected by genomic control, Reus), P-value = 0.0029(passed multiple testing correction, Madrid); OR(95% CI): Reus: 0.64 (0.46-0.89), Madrid: 20.44(2.64-158.24)Dominant More...	Nominal statistical significance was observed as P-value < 0...... Nominal statistical significance was observed as P-value < 0.05 using both control sets under the same genotypic mode. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
AGTR1	angiotensin II receptor, type 1	3q24	1(1/0/0)

SNPs in LD with rs275645 (count: 2) View in gBrowse (chr3:148746667..148760436 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs2934082			0.854[CEU]
rs1492080			1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)