SNP Report

Basic Info

Name	rs2682826 dbSNP Ensembl
Location	chr12:117215033 - 117215033(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.255791
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000317775, ENST00000618760); downstream_gene_variant(ENST00000338101, ENST00000344089)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Buttenschon, H. N., 2004	C/T		Chi-square test or Fisher's exact test, allelic P-value = 0...... Chi-square test or Fisher's exact test, allelic P-value = 0.137, genotypic P-value = 0.276 in total samples; allelic P-value = 0.105, genotypic P-value = 0.209 in British sample; allelic P-value = 0.980, genotypic P-value = 0.045 in Danish sample. More...	The allele and genotype frequencies were very similaramongca...... The allele and genotype frequencies were very similaramongcases and controls in the total and in the British sample. In the Danish sample, we believe that the slight difference in genotype frequencies is due to chance. More...	Positive
Yosifova, A.,2009	A/G		Allelic association: P-value = 0.2 Allelic association: P-value = 0.2	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NOS1	nitric oxide synthase 1 (neuronal)	12q24.22	8(2/5/1)

SNPs in LD with rs2682826 (count: 1) View in gBrowse (chr12:117215033..117217326 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs816361		intron_variant	1.0[CEU]; 0.974[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)