SNP Report

Basic Info
Name rs228697 dbSNP Ensembl
Location chr1:7827519 - 7827519(1)
Variant Alleles C/G
Ancestral Allele C
Minor Allele G
Minor Allele Frequence 0.0603035
Functional Annotation missense_variant; upstream_gene_variant.
Polyphen Annotation: benign(ENST00000614998, ENST00000361923, ENST00000377532, ENST00000613533)
SIFT Annotation: tolerated(ENST00000361923, ENST00000377532, ENST00000613533); deleterious(ENST00000614998)
Consequence to Transcript missense_variant(ENST00000614998, ENST00000361923, ENST00000377532, ENST00000613533); upstream_gene_variant(ENST00000451646)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Yosifova, A.,2009 C/G Allelic association: P-value = 0.46 Allelic association: P-value = 0.46 No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PER3 period circadian clock 3 1p36.23 7(3/4/0)

SNPs in LD with rs228697 (count: 5) View in gBrowse (chr1:7792057..7837168 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)