SNP Report

Basic Info

Name	rs1870736 dbSNP Ensembl
Location	chr15:88081390 - 88081390(1)
Variant Alleles	C/G
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.314297
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000317501, ENST00000355254, ENST00000357724, ENST00000360948, ENST00000394480, ENST00000540489, ENST00000542733, ENST00000557856, ENST00000557897, ENST00000558306, ENST00000558676, ENST00000560017, ENST00000560739, ENST00000626019, ENST00000629765); NMD_transcript_variant(ENST00000558306); non_coding_transcript_variant(ENST00000557897, ENST00000560739)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Athanasiu, L.,2011	G/C		Allelic association: OR=0.9119, P-value = 4.75E-01, P-value(...... Allelic association: OR=0.9119, P-value = 4.75E-01, P-value(trend)=4.85E-01 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q24-q25	2(2/0/0)

SNPs in LD with rs1870736 (count: 4) View in gBrowse (chr15:88064843..88082784 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs16941212	intron_variant; NMD_transcript_variant	0.958[CEU]; 0.928[TSI]
rs16941206	intron_variant; NMD_transcript_variant	0.955[CEU]
rs2349586	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.868[CEU]
rs1966948	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.908[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)