SNP Report

Basic Info

Name	rs16941174 dbSNP Ensembl
Location	chr15:88049218 - 88049218(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.106829
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000317501, ENST00000355254, ENST00000357724, ENST00000360948, ENST00000394480, ENST00000540489, ENST00000542733, ENST00000557856, ENST00000558306, ENST00000558676, ENST00000626019, ENST00000629765); NMD_transcript_variant(ENST00000558306)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Athanasiu, L.,2011	A/G		Allelic association: OR=1.07, P-value = 7.77E-01, P-value(tr...... Allelic association: OR=1.07, P-value = 7.77E-01, P-value(trend)=7.79E-01 More...	Significant associations were found . Significant associations were found .	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q24-q25	2(2/0/0)

SNPs in LD with rs16941174 (count: 4) View in gBrowse (chr15:87953766..88049218 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs8032073	intron_variant; NMD_transcript_variant	1.0[CEU]; 1.0[TSI]
rs12594253	intron_variant; NMD_transcript_variant	1.0[CEU]
rs16941171	intron_variant; NMD_transcript_variant	1.0[CEU]; 1.0[TSI]
rs12101812	intron_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)