SNP Report

Basic Info

Name	rs1425328 dbSNP Ensembl
Location	chr4:21307327 - 21307327(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.167931
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000382148, ENST00000382152, ENST00000447367, ENST00000509207, ENST00000515680, ENST00000515786); NMD_transcript_variant(ENST00000515786); non_coding_transcript_variant(ENST00000515680); upstream_gene_variant(ENST00000382150)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	A/G		P-value=7.11E-05 P-value=7.11E-05	Top 132 SNPs (showing suggestive association to BD in our CA...... Top 132 SNPs (showing suggestive association to BD in our CAMH family cohort: p<0.0001). More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
KCNIP4	Kv channel interacting protein 4	4p15.32	1(0/1/0)

SNPs in LD with rs1425328 (count: 4) View in gBrowse (chr4:21298597..21318389 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs16870742	intron_variant; NMD_transcript_variant	1.0[CEU]
rs16870753	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]
rs16870810	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.874[TSI]
rs10516379	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.874[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)