SNP Report

Basic Info
Name rs1414686 dbSNP Ensembl
Location chr10:54651899 - 54651899(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.0848642
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000320301, ENST00000361849, ENST00000373955, ENST00000373956, ENST00000373957, ENST00000373965, ENST00000395430, ENST00000395432, ENST00000395433, ENST00000395438, ENST00000395440, ENST00000395442, ENST00000395445, ENST00000395446, ENST00000409834, ENST00000414367, ENST00000414778, ENST00000422842, ENST00000437009, ENST00000448885, ENST00000458638, ENST00000495484, ENST00000612394, ENST00000613346, ENST00000613657, ENST00000614895, ENST00000616114, ENST00000617051, ENST00000617271, ENST00000621708, ENST00000622048); NMD_transcript_variant(ENST00000373956, ENST00000414367, ENST00000448885); non_coding_transcript_variant(ENST00000422842)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Hattori, E.,2009 In GWAS: Allelic P-value = 0.00539, Genotypic P-value = 0.01...... In GWAS: Allelic P-value = 0.00539, Genotypic P-value = 0.01429, Recessive P-value = 0.01296, HWE P-value = 0.93162; in Follow-up study: MAF=0.17, Allelic P-value = 0.0062, Allelic Q-value=0.49274, HWE P-value = 0.24396 More... Significant association was observed in both GWAS and Follow...... Significant association was observed in both GWAS and Follow-up study. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PCDH15 protocadherin-related 15 10q21.1 4(2/1/1)

SNPs in LD with rs1414686 (count: 6) View in gBrowse (chr10:54651220..54653644 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)