SNP Report

Basic Info

Name	rs12775630 dbSNP Ensembl
Location	chr10:73443573 - 73443573(1)
Variant Alleles	A/T
Ancestral Allele	A
Minor Allele	T
Minor Allele Frequence	0.023762
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000342558); intron_variant(ENST00000360663, ENST00000394828, ENST00000394829, ENST00000430762)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Forero, D. A., 2016			Nominal P-value=0.001932, Permutation P-value=0.007992,Â OR=...... Nominal P-value=0.001932, Permutation P-value=0.007992,Â OR=2.097, 95%CI=1.301-3.381 More...	Allelic association analysis showed significant results for ...... Allelic association analysis showed significant results for the BP sample with a SNP in PPP3CB (rs12775630; p = 0008) and PRKAR1A (rs4968898; p=0009). More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	10q22.2	2(1/1/0)

SNPs in LD with rs12775630 (count: 1) View in gBrowse (chr10:73443573..73444979 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs35062653		intron_variant	0.825[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)