SNP Report

Basic Info
Name rs12775630 dbSNP Ensembl
Location chr10:73443573 - 73443573(1)
Variant Alleles A/T
Ancestral Allele A
Minor Allele T
Minor Allele Frequence 0.023762
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000342558); intron_variant(ENST00000360663, ENST00000394828, ENST00000394829, ENST00000430762)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Forero, D. A., 2016 Nominal P-value=0.001932, Permutation P-value=0.007992, OR=...... Nominal P-value=0.001932, Permutation P-value=0.007992, OR=2.097, 95%CI=1.301-3.381 More... Allelic association analysis showed significant results for ...... Allelic association analysis showed significant results for the BP sample with a SNP in PPP3CB (rs12775630; p = 0008) and PRKAR1A (rs4968898; p=0009). More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 10q22.2 2(1/1/0)

SNPs in LD with rs12775630 (count: 1) View in gBrowse (chr10:73443573..73444979 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)