SNP Report

Basic Info

Name	rs12441487 dbSNP Ensembl
Location	chr15:88041079 - 88041079(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.216454
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000317501, ENST00000355254, ENST00000357724, ENST00000360948, ENST00000394480, ENST00000540489, ENST00000542733, ENST00000557856, ENST00000558306, ENST00000558676, ENST00000626019, ENST00000629765); NMD_transcript_variant(ENST00000558306)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Athanasiu, L.,2011	G/A		Allelic association: OR=1.382, P-value = 1.94E-02, P-value(t...... Allelic association: OR=1.382, P-value = 1.94E-02, P-value(trend)=1.97E-02 More...	Significant associations were found . Significant associations were found .	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q24-q25	2(2/0/0)

SNPs in LD with rs12441487 (count: 3) View in gBrowse (chr15:88036170..88041079 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs12594283	intron_variant; NMD_transcript_variant	0.902[CEU]; 1.0[TSI]
rs4887204	intron_variant; NMD_transcript_variant	0.902[CEU]
rs12440144	intron_variant; NMD_transcript_variant	0.809[CEU]; 0.821[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)