SNP Report

Basic Info

Name	rs11030119 dbSNP Ensembl
Location	chr11:27706555 - 27706555(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.259784
Functional Annotation	intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000314915, ENST00000395978, ENST00000395981, ENST00000525950, ENST00000530663, ENST00000532997); non_coding_transcript_variant(ENST00000530663); upstream_gene_variant(ENST00000395980, ENST00000584049)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Sears, C.,2011		G	FBAT: MAF=0.28, P-value = 0.003 FBAT: MAF=0.28, P-value = 0.003	Significant association was found . Significant association was found .	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
BDNF	brain-derived neurotrophic factor	11p14.1	37(24/12/1)

SNPs in LD with rs11030119 (count: 8) View in gBrowse (chr11:27645655..27714660 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs1401635	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.914[CEU]
rs10767658	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.844[CEU]
rs11030121	intron_variant; non_coding_transcript_variant	0.914[CEU]
rs7124442	3_prime_UTR_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.914[CEU]; 0.876[TSI]
rs1013402	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.956[CEU]; 0.969[TSI]
rs962369	intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.969[TSI]
rs925946	intron_variant; non_coding_transcript_variant	0.869[CEU]; 0.906[TSI]
rs11030108	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.914[CEU]; 0.969[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)