SNP Report

Basic Info

Name	rs11030107 dbSNP Ensembl
Location	chr11:27673288 - 27673288(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.114417
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000314915, ENST00000356660, ENST00000395978, ENST00000395980, ENST00000395981, ENST00000395983, ENST00000395986, ENST00000418212, ENST00000420794, ENST00000438929, ENST00000499008, ENST00000499568, ENST00000500662, ENST00000501176, ENST00000501663, ENST00000502161, ENST00000525950, ENST00000530686, ENST00000530786, ENST00000530861, ENST00000532997, ENST00000533131, ENST00000533246, ENST00000584049); NMD_transcript_variant(ENST00000530786); non_coding_transcript_variant(ENST00000499008, ENST00000499568, ENST00000500662, ENST00000501176, ENST00000501663, ENST00000502161, ENST00000530686, ENST00000584049)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Sears, C.,2011		A	FBAT: MAF=0.249, P-value = 0.006 FBAT: MAF=0.249, P-value = 0.006	Significant association was found . Significant association was found .	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
BDNF	brain-derived neurotrophic factor	11p14.1	37(24/12/1)
BDNF-AS	BDNF antisense RNA	11p14.1	Mapped by Literature SNP

SNPs in LD with rs11030107 (count: 7) View in gBrowse (chr11:27538197..27679818 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs17309874	intron_variant; non_coding_transcript_variant	0.954[CEU]
rs1401635	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.808[CEU]
rs10835201	intron_variant; non_coding_transcript_variant	0.817[CEU]
rs10835211	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.95[CEU]
rs7481311	intron_variant; non_coding_transcript_variant	0.817[CEU]
rs10767646	intron_variant; non_coding_transcript_variant	0.817[CEU]
rs10767647	intron_variant; non_coding_transcript_variant	0.817[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)