SNP Report

Basic Info

Name	rs10982256 dbSNP Ensembl
Location	chr9:114498554 - 114498554(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.38758
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000480518); intron_variant(ENST00000265134, ENST00000362057, ENST00000374057)
No. of Studies	3 (Positive: 1; Negative: 0; Trend: 2)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Jiang, Y.,2011			Non-weighted test under H0: P-value(additive)=0.00000882, P-...... Non-weighted test under H0: P-value(additive)=0.00000882, P-value(dominant)=0.000585, P-value(recessive)=0.000121; weighted test under H'0: P-value(additive)=0.00000529, P-value(dominant)=0.000351, P-value(recessive)=0.000201; logistic regression: P-value(additive)=0.0000105, P-value(dominant)=0.000411, P-value(recessive)=0.000239 More...	Suggestive association was found. Suggestive association was found.	Trend
The Wellcome Trust Case Control Consortium, 2007	T/C	T	Genotypic P-value = 4.41E-05; Heterozygote OR (95%CI)=1.26 ...... Genotypic P-value = 4.41E-05; Heterozygote OR (95%CI)=1.26 (1.08-1.47); Homozygote OR (95%CI)=1.47 (1.24-1.74) More...	showing moderate evidence of association with BD showing moderate evidence of association with BD	Trend
Ollila, H. M.,2009	C/T		FBAT: P-value = 0.009756 FBAT: P-value = 0.009756	Significant association was observed Significant association was observed	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DFNB31	deafness, autosomal recessive 31	9q32	3(2/1/0)

SNPs in LD with rs10982256 (count: 18) View in gBrowse (chr9:114480295..114513773 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10817625	intron_variant	1.0[TSI]
rs998547		0.921[CEU]; 0.933[TSI]
rs10759710	intron_variant; upstream_gene_variant	0.889[CEU]
rs1408525		0.923[CEU]
rs10982246	intron_variant; upstream_gene_variant	0.886[CEU]; 0.977[TSI]
rs12551529	downstream_gene_variant; intron_variant	0.909[TSI]
rs10982255	downstream_gene_variant; intron_variant	0.96[CEU]
rs4979414	intron_variant	1.0[CEU]; 1.0[TSI]
rs10982268		0.923[CEU]
rs1535962	intron_variant	0.822[CEU]
rs998548		0.815[CEU]; 0.905[TSI]
rs1535960	intron_variant; upstream_gene_variant	0.955[TSI]
rs11789406	intron_variant	0.88[CEU]
rs10817622	intron_variant	0.885[CEU]
rs11787667	intron_variant	0.889[CEU]; 0.864[TSI]
rs10817627	downstream_gene_variant; intron_variant	0.959[CEU]
rs10817626	downstream_gene_variant; intron_variant	0.955[TSI]
rs7034891	intron_variant	0.886[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)