SNP Report

Basic Info

Name	rs1064395 dbSNP Ensembl
Location	chr19:19250926 - 19250926(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.247204
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000252575); downstream_gene_variant(ENST00000291481, ENST00000585410, ENST00000586064, ENST00000588231); upstream_gene_variant(ENST00000624068)
No. of Studies	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cichon, S.,2011		A	For GWAS, P-value = 0.00000342, OR=1.53, for Replication I, ...... For GWAS, P-value = 0.00000342, OR=1.53, for Replication I, P-value = 0.000461, OR=1.23, for combined sample(GWAS+Replication I), P-value = 0.0000000302, OR=1.31 More...	Suggestive association was found. Suggestive association was found.	Trend

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
HAPLN4	hyaluronan and proteoglycan link protein 4	19p13.1	Mapped by Literature SNP
NCAN	neurocan	19p12	1(1/0/0)

SNPs in LD with rs1064395 (count: 24) View in gBrowse (chr19:19248691..19449254 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 24)

rs_ID	Functional Annotation	r²[population]
rs8110171	intron_variant; NMD_transcript_variant	0.811[CEU]
rs2965190	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.898[TSI]
rs2916070	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.811[CEU]; 0.965[TSI]
rs10401714	downstream_gene_variant; upstream_gene_variant	1.0[CEU]
rs4808933	downstream_gene_variant; upstream_gene_variant	1.0[CEU]
rs17216041	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	1.0[CEU]; 0.965[TSI]
rs4808951	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.811[CEU]
rs2965201		0.811[CEU]; 0.965[TSI]
rs2060275	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.811[CEU]
rs4808934	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs2010506	3_prime_UTR_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.933[CEU]; 0.965[TSI]
rs17751061	3_prime_UTR_variant; downstream_gene_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.933[CEU]; 0.965[TSI]
rs2965195	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.811[CEU]; 0.965[TSI]
rs756997	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.811[CEU]
rs11555053	3_prime_UTR_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant	1.0[CEU]; 0.965[TSI]
rs6511027	intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs2011503	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.811[CEU]; 0.965[TSI]
rs2060274	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.811[CEU]
rs10423874	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs8105642	intron_variant; NMD_transcript_variant	0.811[CEU]
rs8110250	intron_variant; NMD_transcript_variant	0.811[CEU]
rs2965186	intron_variant; NMD_transcript_variant	0.965[TSI]
rs10407933	downstream_gene_variant; upstream_gene_variant	1.0[CEU]
rs998732	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.965[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)