SNP Report

Basic Info

Name	rs1054190 dbSNP Ensembl
Location	chr3:119817871 - 119817871(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.0599042
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000337940, ENST00000393716, ENST00000466380); downstream_gene_variant(ENST00000264235); non_coding_transcript_exon_variant(ENST00000493757); non_coding_transcript_variant(ENST00000493757)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Saus, E.,2010	C/T		association analyses with diagnosis: codominant P-value = 0....... association analyses with diagnosis: codominant P-value = 0.993, dominant P-value = 0.997, recessive P-value = 0.907, additive P-value = 0.973 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GSK3B	glycogen synthase kinase 3 beta	3q13.3	8(0/8/0)
NR1I2	nuclear receptor subfamily 1, group I, member 2	3q12-q13.3	Mapped by Literature SNP

SNPs in LD with rs1054190 (count: 0) View in gBrowse (chr3:119817871..119817871 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Saus, E.,2010	association analyses with diagnosis:codominant P-value = 0.521, dominant P-value = 0.393, recessive P-value = 0.547, additive P-value = 0.506	No significant association was observed.	Negative