BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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BioCarta Pathway Report

Basic Info

ID	cdc25Pathway
Name	cdc25 and chk1 Regulatory Pathway in response to DNA damage
No. of Genes in BDgene	2
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
cdc25 and chk1 Regulatory Pathway in response to DNA damage Pathway	PBA paper	Peng, G., 2010	WTCCC	hypergeometric test (Fisher's exact test), Sidak's method, Simes' method, Simes/FDR method	Simes/FDR P-value=0.000786966

Pathway related genes in BDgene (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	22q12.1-q13.1	3(2/0/1)
CDC25B	cell division cycle 25B	20p13	1(0/1/0)